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Cannabis use is associated with psychotic symptoms in between 2% and 21%
of users. The highest rates were reported by experimental studies that
administered tetrahydrocannabinol (THC), while the lowest (2%) were
observed in studies assessing medicinal cannabis.
(URL) https://www.psypost.org/cannabis-use-is-associated-with-psychotic-sym... (https://www.psypost.org)
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|u/Dangerous_Bass309 - 1 month
|
|People predisposed genetically to psychotic disorders, such as if you
|have family members with bipolar or schizophrenia, should not use
|cannabis as it can trigger onset of psychosis. This is not talked about
|enough.
|u/Ambitious-Bit-4180 - 1 month
|
|Yeah, I was diagnosed with schizophrenia and I cannot stretch how much
|Cannabis making me crazy enough. I'm also an abuser of cannabis so
|things got out of hand many times. I had stopped using it for two
|years now and it gets better but sometimes, I just miss Cannabis too
|much, I wish I don't have schizophrenia so that I can vape all the
|cannabis in the world
|u/Dangerous_Bass309 - 1 month
|
|I hope the best for you, stability is key. I have friends and family
|members affected and cannot touch the stuff myself. People are far
|too casual about cannabis now, and unaware of the risks.
|u/Ambitious-Bit-4180 - 1 month
|
|Thank you for your kind words, stranger. I know that stability is
|the key but I just can't control my tendency to abuse cannabis. I
|love cannabis so much it hurts that I can no longer use it now.
|u/liquid_at - 1 month
|
|Has the question about cause vs. self-medication already been answered
|by studies?
|u/HEMORRHOID_JUICE - 1 month
|
|No, but studies do seem to indicate that chronic use of extremely high
|potency products like all day fat wax dabs, might cause psychotic
|disorders. This is especially true if started at a young age. It is
|also worth noting that 2%-21% falls within the global range of
|prevalence of psychotic symptoms. There is other research that
|indicates that if an individual has psychotic symptoms when consuming
|THC they have a 50% chance of developing a psychotic disorder later in
|life. This is not causative but simply observed. I love cannabis
|and have been using it regularly beginning at a young age. I am doing
|great but I would never pretend that it is without risks. It is also
|important to note that high potency THC extracts are a new thing and
|have had some unexpected effects when used chronically.
|u/esaloch - 1 month
|
|Makes sense. I’d imagine you could trigger it with a lot of things
|if you do them in high enough concentrations, there’s caffeine
|induced psychosis for example. The high concentration users are also
|the group that tends to reach the point where it makes them vomit.
|u/OilQuick6184 - 1 month
|
|Just like anything, the dose makes the poison. And up until we
|started concentrating the psychoactive bits it had been relatively
|unfeasible for one to consume a high enough dose to be
|experiencing these types of reactions, along with this, medicinal
|users are much more likely to at least pay attention to their dose
|and attempt to keep it reasonable, whereas I know some
|recreational users who literally smoke dabs all day long. I've no
|idea how they're functioning, but somehow they manage.
|u/senorbolsa - 1 month
|
|I'm curious how much it matters if you have a high natural
|tolerance, I could do that all day, I wouldn't because it's a
|waste, but my body would be fine with it. Though the
|concentration in my blood may be wild.
|u/Ecthyr - 1 month
|
|There' s a very vocal minority who claim that cannabis and other
|psychedelics cannot do any wrong. I am not a hater of cannabis. I
|think it's a recreational drug that can be used in moderation.
|However, the vocal minority is doing a very big disservice to the
|people who are, in fact, having psychotic symptoms, because I see
|examples in my family who do everything to find a root cause of the
|symptoms other than remove/reduce drug use because "weed could never
|do that."
|u/VvvlvvV - 1 month
|
|CHS, a cyclic vomiting syndrome, is cause by daily regular use for
|a long time, like a decade. When doctors tell their stoner
|patients this, they most often don't believe it and don't stop. 
|u/kushhaze420 - 1 month
|
|Even prescriptions have side effects or adverse reactions. It is
|still considered medicine.
|u/MachinaThatGoesBing - 1 month
|
|Prescription drugs are generally a single active molecule
|(occasionally a mix of two active compounds — and even rarer a
|precise combination of more than that, e.g., various
|antiretroviral drug cocktails used to treat or prevent AIDS)
|which is given in a regulated and controlled dose, and which has
|gone through years of rigorous testing to examine efficacy and
|look for side effects or other risks. Proposed prescription
|drugs with serious or dangerous side effects generally do not
|get approval (exceptions being things like chemotherapy drugs
|that target things like cancer that are more dangerous than the
|side effects). If we later find that we missed something when a
|drug was being approved, that approval is generally revoked very
|quickly. Taking something directly from a plant source without
|refinement includes a ton of other potentially active (and in
|this case, specifically some potentially psychoactive)
|compounds, and it makes it really difficult to regulate intake
|so one gets a consistent dose (given the inherent natural
|variability of plants even within a single known cultivar).
|These inconsistencies also make it much more difficult to study
|and determine all the potential effects, and they make it much
|more difficult to create guidelines for safe use. I don't doubt
|that there are potential medical uses of things like THC. But if
|we want to be able to use them in a medical context, we need to
|do rigorous study and create ways for people to get consistent
|and regulated doses from sources with known concentration and
|purity. This *is* something that's already happening, but it's
|not something that a simple joint or edible from a dispensary
|can offer.
|u/Trynapse - 1 month
|
|More difficult to study and assess the full gamet of effects
|in various populations due to the confluence of factors, sure.
|Difficult to regulate intake to obtain a "consistent dose" (or
|effect) and create guidelines for safe use? Not so much. We
|already have those guidelines. Anybody who works in the
|cannabis industry who has gone through something called
|"Responsible Vendor Training" and paid attention to it should
|be able to explain those guidelines. Some states mandate these
|trainings annually. Of course, an experienced or average
|cannabis user can achieve consistent dosing with a joint or an
|edible. Especially an edible of known potency. In fact, I'd
|argue that concentrating cannabinoids only makes it more
|difficult to gauge effects. The potency of any cannabis
|product is determined relatively easily. But even with
|products of highly variable potency, especially flower, and
|especially inhaled, it isn't hard for the user to achieve
|their desired effect. It's as easy as taking a hit and
|waiting. If the 3rd party testing suggests the product is of
|higher than average potency, you take a smaller hit and maybe
|wait longer before taking another one. The most alarming,
|consequential, and perplexing side effect of cannabis known to
|date has to be CHS or cannabinoid hyperemesis syndrome. It's
|quite rare, most likely caused by daily high dose usage and
|symptoms resolve on cessation. It may even be possible to
|determine individual risk based on a genetic test. People who
|develop CHS suffer from abdominal pain and vomiting after
|consuming cannabis. Taking a hot shower temporarily relieves
|or reduces the symptoms. Unfortunately, there is at least one
|case of a young man having developed this who ultimately died
|of dehydration because he continued to abuse cannabis without
|seeking treatment of any kind.
|u/MachinaThatGoesBing - 1 month
|
|> Of course, an experienced or average cannabis user can
|achieve consistent dosing with a joint or an edible. […] >
|> It's as easy as taking a hit and waiting. If the 3rd party
|testing suggests the product is of higher than average
|potency, you take a smaller hit and maybe wait longer before
|taking another one. When I take my blood pressure meds — or
|in the past when I was on SSRIs — I didn't have to take a
|sample dose and then try to gauge my body's reaction in real
|time to figure out how much of the drug I had ingested. I
|knew how much I was getting because it said "50mg" (or
|whatever) on the packaging. Pharmaceuticals are very tightly
|regulated and controlled, and being pure substances, it's
|possible to be highly precise when measuring their
|quantities. If it wasn't having the desired effect, the
|dose would get adjusted *in consultation with my doctor*,
|not on my own. That's what having a consistent,
|predictable, reliable dose means — not having to "eyeball"
|it, trying to individually and subjectively judge your
|body's reaction and self-adjusting an irregular and
|potentially unknown dose on the fly. As much as some
|dispensaries may test things and might even be required to
|test things, for compounds coming from parts of a plant,
|which are already going to be variable, and which are then
|extracted using imprecise means, those numbers will only
|ever be approximate, even if it's a close approximation in
|some cases.
|u/Slothmanjimbo - 1 month
|
|I generally agree and think you have a good point. I would
|recommend also looking into opioids and how extremely
|dangerous they are and the controversy in them getting
|approval to be used as pain management. Those are extremely
|dangerous and have caused so many people a lot of problems in
|a serious way.
|u/Surskalle - 1 month
|
|What? Opioids have been used for pain medication for
|thousands of years. They are very safe when used in a
|medical setting. The controversy is that when a company
|discoveres a new opiod they always market it as 'the non
|addictive opiod' happened with heroin, oxycodone and
|tramadol.
|u/pgpathat - 1 month
|
|People have been addicted to and abusing opioids for
|thousands of years and deciding to package them up and
|sell them as a safe, non-habit forming medicine was an
|evil choice Opioids being safe in a medical setting is
|cool and all but people don’t live in medical settings.
|[That’s why the Opioid crisis is happening in the
|US](https://journalofethics.ama-assn.org/article/how-fda-
|failures-contributed-opioid-crisis/2020-08)
|u/Slothmanjimbo - 1 month
|
|Agree with your point as well, but the opioid crisis in
|the states was caused by deeper issues where the public
|was misled and then gaslit after addictions issues began.
|Here’s a great article to start!
|https://www.hsph.harvard.edu/news/features/what-led-to-
|the-opioid-crisis-and-how-to-fix-it/
|u/Fistulated - 1 month
|
|I have a Cannabis prescription in the UK for my medical
|condition. The other drugs that I am prescribed, give me a
|massive increased risk of multiple different cancers,
|increased risk of multiple sclerosis along with 100 other
|possible horrendous illnesses. I know which one I'm happier
|to be taking
|u/fleebleganger - 1 month
|
|Yup, I take a stimulant for adhd and for me it makes a world of
|difference in being productive but not loopy.  If I took 10 of
|them, I’d be loopy. We’ll, probably not, if I take 2 on accident
|I feel like ahit
|u/7355135061550 - 1 month
|
|As far as random chemical that happen to fit into receptors in
|your brain, weed and some psychedelics are relatively safe. That
|doesn't mean they are free from downsides, contraindications, or
|abuse.
|u/Amaskingrey - 1 month
|
|I saw a couple of peoples who flat out said smoking it was good
|for the lungs. The denial is so deep it goes from frustrating to
|comedic
|u/snajk138 - 1 month
|
|I actually read some meta study that sort of came to that
|conclusion. I don't remember exactly but I think it was that
|people who smoked tobacco had a prevalence of lung cancer at 12
|out of a large group, I don't remember if it was 10K or 100K or
|what though. People who didn't smoke anything was at eight per
|the same amount, and people who used cannabis but not tobacco
|was at six. So less than non-smokers. I don't remember the
|number for people who smoked both though. My guess is that the
|group that uses cannabis but doesn't smoke might be more healthy
|in other areas than the population at large, like more active or
|vegetarians or so, but the more unhealthy cannabis users will
|also smoke tobacco to a larger extent. This was a few years ago
|though, it might have changed since cannabis started to become
|more legal.
|u/xfusion14 - 1 month
|
|The only thing you can safely say is that weed itself can’t kill
|you or overdose. Things people do to it is where u have a problem.
|u/legendary_mushroom - 1 month
|
|Weed can't, maybe, but what about concentrates?
|u/Amaskingrey - 1 month
|
|No, it absolutely can. Firstly through physical injuries due to
|weed making you less aware and more sluggish thus more likely to
|fall, secondly via the psychosis it can cause, and thirdly
|overdose leading to respiratory distress is possible (albeit
|requiring such a huge amount and low tolerance that it happens
|almost exclusively in accidental ingestions)
|u/Trynapse - 1 month
|
|No, we absolutely can not answer that question with any
|certainty (and I'll provide a [reference](https://apm.amegroup
|s.org/article/view/23880/html)). There are only two widely
|known (as reported in medical literature) deaths where
|cannabis was implicated and could not be ruled out as a
|"cause." But those deaths were still very mysterious, and
|cannabis likewise could not be implicated beyond any
|reasonable doubt. In other instances there were clearly
|comorbitities- most commonly heart conditions. There goes
|speculation #3. Psychosis isn't death, is oft-enough
|treatable or not permanent and again, there are far too many
|unresolved questions where cannabinoids and psychiatric
|symptoms are concerned. These range from general correlation
|vs causation conundrums, to deeper questions about how
|specific cannabinoids interact with the endocannabinoid
|system. E.g. reserch on CBD suggests it may act as an
|antipsychotic. It was put up in one study against risperidone.
|As for "physical injuries due to weed making you less aware
|and more sluggish...more likely to fall". This just sounds
|like an almost stereotypical assessment of the intoxicating
|properties of cannabis. Yet, the same could be said for any
|intoxicant. This is notable considering most cannabis
|consumers would describe the effect as most typically being
|somewhat to significantly less intoxicating than alcohol. Of
|course, for purposes of root cause analysis the cannabis would
|virtually always be considered a contributing factor; not the
|cause. This is to really all just to say that a reasonable
|individual consuming your typical legal cannabis products
|simply isn't going to have harm like that come on them all of
|a sudden. Don't be a moron and eat a 500 mg TAC serving of
|edibles in one sitting without knowing you can handle that
|(and most certainly can't but it won't kill them).
|u/Nicolai01 - 1 month
|
|I was very preachy about psychedelics myself after trying it for
|the first time. If you have a positive experience, it's such a
|mindblowing and beautiful experience that you want everyone to go
|through it. As positive and beautiful a psychedelic experience
|can be though, it can go exactly as much in the other direction,
|being a complete nightmare experience, which I've also tried. I
|still wish I was legally allowed to choose what I can put in my
|own body though. I wish you could choose to get educated about
|specific drugs and then weight the positives and negatives
|yourself or with guidance.
|u/cenobitepizzaparty - 1 month
|
|There's not, though. Every time this topic comes up, someone says
|that literally unprompted. The only thing people hate more than
|someone enjoying weed in their life with no issues is minding
|their own business
|u/DaRealWhiteChocolate - 1 month
|
|I've also seen threads here where the comments act like it's
|god's gift to mankind, and no one takes a moment to criticize
|it. I don't think people mentioning how frustrating this is are
|not "minding their own business," it's a completely valid
|observation.
|u/papapoptarts - 1 month
|
|It’s a completely valid observation, but also a redundant and
|unnecessarily pointed observation. Every adult function I
|have been to since 21 involves - revolves around - alcohol. We
|glorify drugs, it’s a problem. It doesn’t mean cannabis has
|some kind of special badness, it just means people get a
|little too excited and hopeful about their drugs. People talk
|about SSRIs the same way if they get a benefit from it. SSRIs
|destabilized my life, and it took a massive medical
|intervention to get me back on track. It would be silly for
|me to constantly observe that SSRI patients only ever talk
|about their positive experience instead of my (valid)
|nightmare experience.
|u/DaRealWhiteChocolate - 1 month
|
|If it's "redundant and unnecessarily pointed observation"
|then so is this comment, no? It's well known that a lot of
|people have issues with SSRI's. I'm one of them.
|u/cenobitepizzaparty - 1 month
|
|You're just reinforcing what that person said while ignoring
|the validity of my statement because you agree with them.
|Doesn't mean I'm not valid.
|u/DaRealWhiteChocolate - 1 month
|
|Why does it seem like you take this personally, even more so
|now that I've commented on it? I never said your input was
|invalid. If you have no issues, but others do, why do such
|statements need to upset you in the first place?
|u/cenobitepizzaparty - 1 month
|
|I love the reddit tactic of acknowledging my response by
|saying I'm upset because I responded. Am I not supposed to
|respond or what? Again, deflecting my original sentiments
|to instead delve into why I'm allegedly upset.
|u/DaRealWhiteChocolate - 1 month
|
|So you comment on an article about psychotic symptoms in
|cannabis users, clearly bothered by the topic at hand,
|to make an out of context comment about people "just
|enjoying cannabis with no issues" despite the original
|comment being relevant to the topic at hand of cannabis
|causing documented issues? How is the original comment
|unprompted in this context? I feel like there's a lot of
|people who get defensive about what cannabis does or
|doesn't do for them in terms of negatives because it
|makes them feel good and acknowledging potential issues
|gets in the way of the cognition that "it helps them
|with no issues." Nothing is free of problems, natural
|or pharmaceutical. Acknowledging when something has
|drawbacks is one of the easiest paths to ensuring you
|are making the best decisions for your physical and
|mental health.
|u/cenobitepizzaparty - 1 month
|
|How is my comment out of context? You're all over the
|place dude. I'm over it.
|u/No-Tension-4730 - 1 month
|
|Regardless of no experienced issues it's still
|objectively neurotoxic. So no you do have issues with it
|you just aren't aware of what it is or how it's
|effecting you or will effect you. This isn't am opinion
|this is a fact, the amount of cognitive dissonance
|associated with weed from people coping about how it
|does no harm to them is objectively dumb not
|subjectively. I'm not saying it's alcohol or meth but
|bulls*it it doesn't cause harm that's blatantly false.
|u/cenobitepizzaparty - 1 month
|
|A toxin that your body was made to receive. You guys
|really just want to be right about everything by
|speaking in generalizations, which makes as little
|sense as the idea of you minding your own business
|u/Dragonfly-Adventurer - 1 month
|
|These folks have never talked to an emergency room physician in a
|children's hospital.
|u/ShaiHulud1111 - 1 month
|
|Is there an epidemic. Just curious.
|u/Amaskingrey - 1 month
|
|Yeah, a few health organisation (the FDA and canada's) had to
|issue warnings after several cases of kids/teens overdosing on
|edibles thinking they were regular candies
|u/ShaiHulud1111 - 1 month
|
|But, you can’t overdose. It’s not toxic. I guess a mental
|break is possible and the very rare “it gave them
|schizophrenia “ case, but a few hard drinks will kill a
|kid,but never heard of a death from pot. You say overdose as
|took more than they could cope with, but nobody was at risk
|of serious injury. Yes, I am going to die on this hill.
|u/Amaskingrey - 1 month
|
|Well first off you can overdose over anything; everything
|is toxic in sufficiently large quantity, ever heard of
|water poisoning? And it can't give schizophrenia by
|itself, however it can cause it to become active early in
|those who have a latent form of it. And while there hasnt
|been any known deaths from cannabis products thanks to the
|symptoms being really obvious, with ludicrous doses that
|are only really achievable with accidental consumption of
|edibles it can have enough of a relaxant effect to affect
|the control of the lungs, leading to respiratory distress
|(also the fairly obvious possibility of just falling down
|the stairs due to being stoned and breaking your neck)
|u/darctones - 1 month
|
|Partially because studies are limited since marijuana is a Schedule
|1 drug with “no accepted medical use and a high potential for
|abuse”. It is literally in the same category as heroin and higher
|than cocaine or fentanyl. That is the true disservice here.
|Marijuana needs to be rescheduled to at least codeine (III) or Xanax
|(IV)
|u/NotReallyJohnDoe - 1 month
|
|Xanax, the drug that can cause blackouts, kill you if you combine
|it with alcohol, and can also kill you with withdrawals? That
|should be scheduled like cannabis which essentially can’t possibly
|kill you?
|u/InconspicuousIntent - 1 month
|
|Sounds like the two should switch places in classifications.
|u/NotReallyJohnDoe - 1 month
|
|Cannabis shouldn’t be scheduled. It’s less harmful than
|alcohol.
|u/Hanifsefu - 1 month
|
|They are afraid that after all the facts come out and it isn't
|actually the murder and mayhem causing super gateway drug that
|makes you addicted to heroin and cocaine before you ever touch
|them then they'll have to let a lot of free labor out of their
|cells and the shareholders will lose money.
|u/darctones - 1 month
|
|And it prevents cops from saying: I smell weed, which is
|essentially heroin, so straight to jail.
|u/HelpfulSeaMammal - 1 month
|
|Helps get rid of this particular flimsy excuse to search your
|property without having any other justification for probable
|cause or a warrant. "I smell chocolate chip cookies. Now
|it's not illegal for us to search and seize your property
|because we have reason to suspect a crime has occured." Sounds
|kind of ridiculous, especially when you replace "chocolate
|chip cookies" with marijuana.
|u/JustDoc - 1 month
|
|>It is also important to note that high potency THC extracts are a
|new thing and have had some unexpected effects when used
|chronically. Exactly. It would be really interesting to see a
|study that compares the long-term outcomes of participants that
|smoke dried ground plant material vs. those that smoke
|extracts/carts. I suspect that you'd see higher incidents of
|cannabis induced psychosis and other issues in the latter group due
|to the ease of consumption, but it's hard to say one way or the
|other without actual (well run) research.
|u/puravida3188 - 1 month
|
|It’s also not just a simply binary between plant/extract. Among
|extracts different processes will result in different products as
|evident by their texture and composition. Also the cannabinoids
|are only part of the story, the role of terpenes and other
|secondary metabolites are often not considered in these studies.
|u/liquid_at - 1 month
|
|I think most of the research on developing brains has shown that it
|can be harmful. Imho, there needs to be a distinction between
|developing and fully formed brains. I agree on extracts. Many are
|far too potent and despite existing for decades, there is hardly any
|data at all.
|u/PM_Me_Your_Clones - 1 month
|
|Try more like [eighty years, during
|WWII](https://www.nytimes.com/1977/09/05/archives/files-show-
|tests-for-truth-drug-began-in-oss-marijuana-derivative.html). Of
|course, you had to be a spook, and then Hofman and his bike ride
|changed the game, so we're getting more real empirical knowledge
|now.
|u/somedude1592 - 1 month
|
|This is inaccurate. There’s very little evidence that it causes
|psychotic disorders, but it can make people predisposed to psychosis
|encounter it sooner and have a worse “trajectory.” Dr. Matthew
|Hill, a leading researcher on the effects of cannabis, discusses
|this topic at length [as a guest on the Huberman Lab
|Podcast.](https://www.hubermanlab.com/episode/dr-matthew-hill-how-
|cannabis-impacts-health-the-potential-risks?timestamp=7625) Edit to
|include a more nuanced quote from the actual research article-
|“Third, not every individual exposed to cannabis is equally at risk
|of CAPS as the interplay between individual differences and the
|pharmacological properties of the cannabis likely play an important
|role in modulating risk.”
|u/puterTDI - 1 month
|
|You state this is incorrect, but their statements seems to be
|consistent with what is described in the paper. Are you saying
|the paper is inaccurate as well?
|u/somedude1592 - 1 month
|
|The paper doesn’t do a good job clarifying causality and/or
|adding this nuance. I wouldn’t say that it’s outright incorrect,
|but the lack of explanation can lead to incorrect conclusions
|like the person above me posted. Just as an example, if
|cannabis use caused psychosis, we would see increased rates of
|psychotic disorders in places with higher cannabis use, and we
|would likely notice an uptick when a state or country legalizes
|cannabis. We haven’t seen that though, it just appears to affect
|the trajectory of those who were likely to experience psychosis
|at some point anyways. The podcast I linked to gives more
|examples like this along with fully explaining what we can and
|can’t conclude from the research.
|u/HEMORRHOID_JUICE - 1 month
|
|This is exactly why I noted that the range of 2%-21% falls
|within the global range for prevalence of psychotic symptoms
|within different populations. This is also why I answered "No"
|to the question I was responding to. Most people who use
|cannabis do not consume wax all day. This is a new phenomenon
|and we are only just now starting to research the effects.
|u/somedude1592 - 1 month
|
|So your comment was just misleading then? High potency (wax)
|or low potency (traditional smoking), it still does not
|cause psychotic disorders in those without a predisposition
|and/or those who weren’t likely to develop a psychotic
|disorder at some point in their life anyways.
|u/HEMORRHOID_JUICE - 1 month
|
|Not at all. What I am saying is the newer research on high
|frequency high potency THC product consumption is
|beginning to look different from old research. This is
|starting to point to something that might be considered
|causative. We need more time to understand fully but it is
|clear that there are some differences worth exploring in
|these different groups of consumers. We simply do not know
|and there is enough doubt to make your statement untrue.
|Also important to note that predisposition does not equal
|having a disorder. you can be predisposed to something
|and not get it. Some people are predisposed to diabetes,
|if they eat a healthy diet low in sugar, they might not
|get it. If they live on soda they might get it.
|u/somedude1592 - 1 month
|
|Also, in your analogy with diabetes you would expect for
|us to see higher rates of diabetes in areas with poor
|nutrition and lifestyle factors. This would affect those
|predisposed to diabetes and those who aren’t
|predisposed, leading to higher overall rates of
|diabetes. in those situations, we can conclude that
|nutrition and lifestyle factors play a role. That
|isn’t the case with cannabis and psychotic disorders
|though. We would expect to see a higher prevalence of
|psychotic disorders in places that had higher rate of
|cannabis use, and that simply isn’t the case.
|u/HEMORRHOID_JUICE - 1 month
|
|This is the end of it for me. Do some research and you
|will see that in the last 5 years, new data is coming
|to light that warrants further exploration. This is
|not about cannabis use but about high potency chronic
|use. This type of use does not necessarily go up When
|cannabis becomes legal or more widely used. [https:
|//www.nature.com/articles/s41398-022-02112-8](https://
|www.nature.com/articles/s41398-022-02112-8)
|u/somedude1592 - 1 month
|
|A lack of evidence doesn’t mean something is true. You
|are the one making the claim that it can cause psychosis
|without providing any evidence. And I do agree that more
|research needs to be done, but what you’re claiming
|still isn’t clear the in the existing research. Do you
|have links to any peer reviewed articles of this “new
|research” that specifically identify cannabis as a cause
|of psychotic disorders? Because expert scientists in the
|field disagree with your claim as of a month ago.
|u/HEMORRHOID_JUICE - 1 month
|
|I have read it and I encourage you to go search for
|yourself. I gave you one journal article already. I
|don't have time to continue. As I said, I will go
|listen to that podcast but that is not a peer reviewed
|study. I am not making this claim that you keep on
|trying to dispute. I don't really know what else to
|say. I am trying to be nice but this seems like a
|comprehension issue on your part. Don't just Google,
|search the literature using libraries or other
|databases. I never said a lack of evidence makes
|something true. I said that you are making an absolute
|statement but that is an Untrue statement because
|there is enough doubt and research pointing to a need
|to explore more. This is what science is about. You
|seem hell bent on this being settled fact and it being
|impossible that a new relationship with the drug might
|pose new issues.
|u/Pineydude - 1 month
|
|Some of the flower now is over 30%. That’s getting into
|the old school concentrate- hash territory. In all for it
|. Don’t be stupid is all. Higher concentration means less
|smoke inhaled. I do not mess with wax or dabs though.
|u/probablynotnope - 1 month
|
|Try to transition to edibles, if you can. Smoking anything
|habitually is a strain on the heart and lungs.
|u/HEMORRHOID_JUICE - 1 month
|
|Thanks! I have not smoked in a long time. I switched to edibles
|and the occasional vape over a decade ago and it made a huge
|difference. no more waking up wheezing...
|u/probablynotnope - 1 month
|
|Make sure to lightly remind people. An unfortunate contingent of
|pro-mj people hold bizarre views like it prevents lung cancer
|because "natural". I mean...it's still burning organic matter.
|u/unicornofdemocracy - 1 month
|
|prevelance of psychotic symptoms is 2-21%?!?! Never ever heard of
|that statistic before.
|u/grimorg80 - 1 month
|
|To me the paper simply supports a correlation. It sounds like they
|add to the existing literature saying that THC in general doesn't
|generate psychosis, but it makes psychotic episodes more possible in
|predisposed patients
|u/artofcannabis - 1 month
|
|I’m really interested in seeing studies on this, and also how many
|patients with psychosis were consuming products grown with
|pesticides and other harmful chemicals. Not saying THC on its own
|can’t cause this- but I’d be interested to see if that has any
|bearing.
|u/Consistent_Bee3478 - 1 month
|
|I mean that THC on its own has a massive risk of triggering
|psychosis is a fact. The partial antagonism of CBD at the
|appropriate receptor is required to eliminate that risk. Hence
|studies using pure THC even in not so high doses showing high rates
|of psychosis, whereas medical cannabis studies with balanced THC/CBD
|consumption don’t. 
|u/drunk_haile_selassie - 1 month
|
|There's studies that have shown that almost 30% of people with ADHD
|have cannabis use disorder. Unfortunately, it's almost entirely self
|medication.
|u/somedude1592 - 1 month
|
|It’s very hard to say anything has been “answered” at this point, but
|experts in this area have pointed at this exact thing to explain why
|rates of psychosis or psychotic disorders aren’t correlated with
|cannabis use across populations. A lot of people in in the comments
|are saying that cannabis can cause psychosis, and this just isn’t
|true, unless someone is predisposed to psychosis and is already likely
|to experience a psychotic episode at some point in their life. We do
|know that it can make symptoms of psychosis show up earlier and make
|them worse for people who are predisposed, but there is little to no
|evidence to show that it outright causes psychosis or psychotic
|disorders. For anyone who want to learn more from an expert
|researcher in this domain, [I recommend listening to the Hubermanlab
|episode where Dr. Matthew Hill explains this nuance in
|detail.](https://www.hubermanlab.com/episode/dr-matthew-hill-how-
|cannabis-impacts-health-the-potential-risks?timestamp=7625)
|u/liquid_at - 1 month
|
|Thank you for the link! But yes, that is why I am asking. A lot of
|people claim it can cause issues, other claim it can't.... But
|research is the only thing I trust.
|u/somedude1592 - 1 month
|
|Agreed! Cannabis isn’t without its share of problems and/or health
|risks, but outright causing psychosis is not one of them.
|u/IamTheEndOfReddit - 1 month
|
|In some areas, like schizophrenia. People in countries with lower
|cannabis consumption don't have lower rates of schizophrenia. Cannabis
|promotes 'positive' side effects like creation of hallucinations, but
|helps with negative side effects that schizophrenia meds don't
|address. People predisposed to schizophrenia also have a higher rate
|of cannabis use before getting schizophrenia, it seems the genes that
|cause schizophrenia also promote early weed consumption
|u/colorfulzeeb - 1 month
|
|Conditions like schizophrenia and other psychotic disorders have an
|onset. Usually a stressful life event which is likely why the onset
|is often late teens to around thirty, which is usually when there’s
|a lot of stress from life transitions. For some, cannabis is the
|stressor or trigger. So rates of schizophrenia wouldn’t necessarily
|change based on weed consumption, but the onset age would
|potentially differ. Though you would likely see large correlations
|to onset age in numerous other areas when comparing populations of
|different countries. This is based on the theory that it’s linked
|only to onset of schizophrenia, rather than being causative of
|psychotic disorders. If it was causative, you’d assume there would
|be higher rates in countries with high rates of cannabis
|consumption.
|u/IamTheEndOfReddit - 1 month
|
|I don't think that's true, the scientist I was listening to would
|have mentioned later onset of schizophrenia in low-cannabis
|countries. The onset event might be unaffected in its likelihood
|by weed even if weed may affect the event. I don't really doubt
|the destabilizing potential of weed but we need a new story when
|the data doesn't fit
|u/colorfulzeeb - 1 month
|
|I know; it may not be, and we never knew it to be fact, given
|that the lack of research on cannabis has been a long-standing
|issue. I was just explaining the theory and how it relates ti
|what you’re saying vs cannabis being causative. Not having
|higher rates of schizophrenia in countries with higher weed
|consumption would support this theory, but more studies would
|need to be done to compare and make this information meaningful,
|if that’s the case. That research or any other new studies could
|totally disprove this theory. TBD.
|u/IamTheEndOfReddit - 1 month
|
|Yeah it's a super interesting combination
|u/Smee76 - 1 month
|
|Yes, it is causative.
|u/Frumplefugly - 1 month
|
|I smoked for years and was fine and one day the psychosis kicked in and
|i was admitted to the psych ward for a month. Fun times
|u/Due-Science-9528 - 1 month
|
|How old were you when that happened
|u/EaseofUse - 1 month
|
|I don't understand the article, where is it implying the 'psychotic
|symptoms' last for longer than the high the user is experiencing? It
|notes some people have lasting issues with schizophrenic symptoms after
|usage, but that's already generally known, and has the same
|complications of drug usage dovetailing with the time (age 19-22) when
|most mental illnesses tend to manifest. And that's not part of this
|study, anyway. It seems more like its noting the unpleasant effects
|some people experience *in the moment* while high on the drug and then
|loosely associating it with the *THIS WILL RUIN YOUR BRAIN FOREVER*
|fearmongering of releasing latent schizophrenic dysfunction.
|u/SynexEUNE - 1 month
|
|It does not. It says caps( cannabis-associated psychotic symptoms),
|acute. So getting a bad high has most certainly been taken into the
|results more then once in this meta study. If cannabis would cause
|psychosis in 20% of the population , we would have seen this in
|healthcare long ago.
|u/Due-Science-9528 - 1 month
|
|Psychotic symptoms and psychosis are not the same thing
|u/tEnPoInTs - 1 month
|
|I mean I've kind of had this happen where it will very occasionally
|trigger a panic attack that may last like 2-3 hours where the euphoria
|wears off in like 1.
|u/itsalongwalkhome - 1 month
|
|It's because thc can be stored in fat. I got told to quit medical weed
|before starting stimulants by my psych because of this .
|u/Brrdock - 1 month
|
|But it doesn't do anything in the fat, it's not active. It's
|released into the blood to be filtered out over weeks, but in such
|miniscule quantities it's completely irrelevant. Like eating 1/1000
|of a gummy. Seems like a misunderstanding or just overcaution.
|u/itsalongwalkhome - 1 month
|
|Even her understanding was over caution, but they want to be over
|cautious with stimulants.
|u/LeucotomyPlease - 1 month
|
|like before taking adderrall? yeah that’s not necessary. just some
|anti-weed bias some doctors have.
|u/itsalongwalkhome - 1 month
|
|She said it was a minuscule risk of increasing the chance of
|psychosis, the fact that weed itself increases the risk of
|psychosis makes it understandable that they don't want to add
|additional drugs to that.
|u/lesath_lestrange - 1 month
|
|In order for me to continue my Adderall prescription while
|smoking the amount of marijuana I do. My doctor encourages me to
|cheat on the urinalysis that I am required to take by the
|hospital system that he works under. My understanding is that
|while there is some pushback within this specific hospital
|system about the interactions between Adderall and cannabis it
|is not their recommendation for my medical treatment to stop
|either. For my treatment, they would prefer me to go see
|another doctor and continue the same medications rather than be
|denied both medications because of the hospitals bureaucracy.
|Or, like I said, cheat on the urinalysis to continue seeing the
|same provider.
|u/Bridgebrain - 1 month
|
|You're not wrong, but in general its a good idea to be on one
|thing at a time when you're starting meds so you can tell what is
|doing what. Multiple meds interacting makes seeing whether its
|working properly or not much more difficult
|u/LeucotomyPlease - 1 month
|
|counter point - you’re a regular weed smoker for years and then
|your doctor says “quit cold turkey at the same time you are
|starting a brand new medication” … how would you be able to
|tell withdrawal symptoms apart from side effects of the new
|medication? you can’t.
|u/Bridgebrain - 1 month
|
|I mean, mine required me to get off for a month before
|prescribing me something, so...
|u/myboybuster - 1 month
|
|I'm not saying that what I experience is similar to what this study is
|saying, but I have experienced getting too high and it being sent into
|a moths long bout of existential panic. Completely disassociated and
|unable to enjoy life
|u/LilacHeart - 1 month
|
|My sibling ended up in a psych ward for a month because of THC build
|up in their brain. They were smoking a lot in a state where
|recreational weed was fully legal and now they’re advised to never
|smoke again. I doubt it’s very common but because of that I also limit
|my weed.
|u/NotReallyJohnDoe - 1 month
|
|“THC build up in the brain”. What does that even mean?
|u/LeucotomyPlease - 1 month
|
|“THC build up in the brain” is not a thing that lands people in a
|psych ward. perhaps your sibling had pre-existing mental illness
|that heavy marijuana use wasn’t helping, but it does not *cause*
|schizophrenia or bipolar-polar mania.
|u/cemilanceata - 1 month
|
|Yes this is the same as alcohol cause psychosis when consumed, the
|"drunk" and "high" is a form of psychos
|u/ChronicallyPunctual - 1 month
|
|I self medicate due to severe depression. My depression can sometimes
|make me feel psychotic, but damn is the weed helping. My wife can take
|one puff and have weird manic episodes, so each person is way different
|with weed.
|u/TheParagonLost - 1 month
|
|The direction of causality is the issue here. Is it that cannabis causes
|psychotic symptoms or those with psychotic symptoms are at a greater
|risk of drug abuse. We don't know the former, but we definitely know the
|latter is true.
|u/forbutamomentintime - 1 month
|
|But also even if cannabis is not the root cause of the issue, if it
|only triggers the psychosis they were predispositioned for, how do we
|know who is at risk? And is it worth the risk with that much unknown?
|Even if eventually you may go psychotic, would you rather have 5, 10,
|15 years or more without being psychotic? Would you rather have less
|psychosis? In dealing with psychotic patients, I promise they and
|their families would wind back the clock and avoid any trigger they
|could. It is always a sad situation as you watch people grieve their
|lives and what could have been vs what is. Psychotic disorders are no
|joke.
|u/ayatollahofdietcola_ - 1 month
|
|> if it only triggers the psychosis they were predisposition for,
|how do we know who is at risk? We don’t. The only thing we have
|is information about our parents, grandparents, and whether they had
|schizophrenia or had other psychotic symptoms. And unfortunately,
|a lot of our parents have not been honest with us about who heard
|voices, had schizophrenia, had post-partum psychosis, or bipolar
|disorder with psychotic symptoms. The most at-risk group are
|males between the ages of 18-25 who smoke frequently. But it also
|just so happens that 18-25 year old males are stubborn as mules
|There is a very good reason why they have been trying to discourage
|young people from frequent marijuana use in that age range, it’s
|because it can trigger psychosis, and you have no reliable way of
|looking into your brain and knowing what you’re predisposed of
|u/snajk138 - 1 month
|
|Sure, but it could be the opposite as well, right? Maybe cannabis
|delays the outbreak of psychosis due to the calming effect or
|something. That's what the "medicating" part is of "self
|medicating".
|u/b88b15 - 1 month
|
|We should simply do a randomized, prospective study. Not possible to
|do placebo here. But, there are enough legal recreational states that
|this could be accomplished, say via 5 mg QD at night every night for a
|year, and have a control arm that takes melatonin or something.
|u/hoolsvern - 1 month
|
|How were those experimental doses of THC administered? What was the
|dosage? This appears to have been a literature review and I’m sure that
|the actual published study has useful information but this summary is
|way too sparse on methodology to actually compare any statistics between
|cohorts.
|u/zeptillian - 1 month
|
|"symptoms can include hallucinations, delusions, and disorganized
|thinking" Isn't that specifically what psychoactive substances do?
|u/CitizenLoha - 1 month
|
|Well, I am one of those. Twice used it, and twice had a horrible
|experience. The second one was the absolute worse: I was completely
|out of my mind paranoid and I could hear the TV next door talking to me
|and telling me to do very bad things.
|u/Warm_Iron_273 - 1 month
|
|That eventually goes away if you abuse the drug for long enough. In
|fact, now I'm anxious, depressed and paranoid when I'm NOT high, now
|that my brain has rewired itself for dependence. A real win if you ask
|me!
|u/CitizenLoha - 1 month
|
|No thx. Twice was enough. Don't need to try that anymore.
|u/____ozma - 1 month
|
|Does someone with more knowledge than I on the topic know how often or
|if at all these studies are replicated? Reading "the results of each
|study varies greatly" and numbers like 2-21% say less to me about the
|results themselves and more about the quality of studies or difficulty
|conducting them. It's hard to walk away from something like that with
|anything but more questions.
|u/berrylakin - 1 month
|
|It's going to be a few years after cannabis becomes federally legal
|before we really start truly understanding this plant in my opinion.
|u/HappyInstruction3678 - 1 month
|
|It feels like no matter what they learn, the answer should already
|be obvious. Don't smoke weed all day, every day or you'll eventually
|have problems. I say this as somebody who is a regular user.
|u/BlackExcellence19 - 1 month
|
|I feel like I talk a lot slower and struggle to complete my sentences as
|sharply as if I had lost some of my vocabulary but not sure I’m still
|pretty young so I can blame it on either depression or weed
|u/Icy-Gap2745 - 1 month
|
|Try not using and see how that goes w/ your vocabulary. If you’re
|using because you are depressed, without therapy along with the trees,
|you could be making yourself worse.
|u/BlackExcellence19 - 1 month
|
|Yeah I wish I could try not using but I’m definitely addicted to it
|at this point BUT I’d say I’m more of a functional addict since I
|only take 1-2 edibles a day at night and none throughout the day
|u/Icy-Gap2745 - 1 month
|
|That doesn’t sound like a lot. In that case, try considering gaps
|in your diet and level of physical activity. You could be
|vitamin/mineral deficient or simply just not moving your blood
|throughout your body enough, which will reduce your mental
|sharpness. *not a doctor*
|u/StonksNewGroove - 1 month
|
|I think part of the issue is potency. Today’s marijuana is so strong and
|concentrated. We haven’t really learned what introducing that much
|dopamine release all at once does to the brain over time.
|u/sorped - 1 month
|
|Add to that volume. When igensting stronger edibles, you're basically
|eating the equivalent of smoking several joints at a time.
|u/ThaNeedleworker - 1 month
|
|It’s not dopamine
|u/StonksNewGroove - 1 month
|
|Yes it is, cannabinoids encourage the release of dopamine into your
|brain. Dopamine isn’t the active ingredient in marijuana that causes
|a “high” but it’s what the brain releases when introduced to
|cannabinoids.
|u/ThaNeedleworker - 1 month
|
|I’m just saying that the amount of dopamine isn’t what is
|concerning. We’ve seen what happens with dopamine release with
|amphetamines and other stimulants. We’ve never seen what happens
|with the amount of phytocannabinoids
|u/Dennygreen - 1 month
|
|I tested it. it's fine
|u/somedude1592 - 1 month
|
|To add some nuance for those without a ton of experience with this
|research- research so far has shown that cannabis does not cause
|psychosis in individuals unless they were already highly predisposed to
|psychosis. With that said, it can cause symptoms of psychosis to appear
|earlier and be worse than they otherwise would be. [Dr. Matthew Hill
|talks about this at length on the Huberman Lab
|podcast](https://www.hubermanlab.com/episode/dr-matthew-hill-how-
|cannabis-impacts-health-the-potential-risks?timestamp=7625)
|u/SaltyPinKY - 1 month
|
|It's hard to take something serious when it says "between 2% and
|21%"........
|u/Kryptonite-- - 1 month
|
|Did you read more than the title / headline?
|u/SaltyPinKY - 1 month
|
|Yes....and it's still not worth taking serious. The only
|difference between medical cannabis and recreational is testing for
|pesticides and chemicals used in feeding.
|u/e_hota - 1 month
|
|Recreational weed is tested in legal states, too. Depends how
|you’re defining “recreational”
|u/tehwagn3r - 1 month
|
|While the association has been well documented for long: >However, we
|found no evidence of an effect of cannabis on Psychoticism or any of its
|facets in co-twin control models that compared the greater-cannabis-
|using twin to the lesser-using co-twin. >We also observed no evidence
|of a differential effect of cannabis on Psychoticism by polygenic risk
|of schizophrenia. Although cannabis use and disorder are consistently
|associated with increased risk of psychosis, the present results suggest
|this association is likely attributable to familial confounds rather
|than a causal effect of cannabis exposure. >Efforts to reduce the
|prevalence and burden of psychotic illnesses thus may benefit from
|greater focus on other therapeutic targets. [Adolescent cannabis use
|and adult psychoticism: A longitudinal co-twin control analysis using
|data from two
|cohorts.](https://psycnet.apa.org/doiLanding?doi=10.1037%2Fabn0000701)
|u/slintslut - 1 month
|
|Some reefer madness bull-ish going on today, this is the 5th negative
|post about weed I've seen today
|u/EvenOne6567 - 1 month
|
|Oh no studies being done about the negative effects of thc so that
|people are informed, I should definitely listen to redditors claiming
|weed has zero downsides whatsoever Instead!
|u/Remarkable-Motor7705 - 1 month
|
|He just spent $12 million to oppose Florida’s cannabis legalization.
|And all the anti-weed Redditers are loving every second of it
|u/Chrome-Depot - 1 month
|
|There's a difference between being anti-weed and accepting that
|there may be some negative effects associated with weed. I smoked
|daily for over 20 years but recently quit because the negatives
|have started to outweigh the positives for me. I'm not anti-weed
|but I'm honest with myself about how it affected me
|u/NotReallyJohnDoe - 1 month
|
|All 2 of them?
|u/wanderingstargazer88 - 1 month
|
|Weed *can* cause psychosis but it's entirely dependent on the
|individual using it. But even then it's pretty rare.
|u/mvea - 1 month
|
|I’ve linked to the news release in the post above. In this comment, for
|those interested, here’s the link to the peer reviewed journal article:
|https://www.nature.com/articles/s44220-024-00261-x From the linked
|article: An analysis of numerous studies on cannabis use revealed that
|between 2% and 21% of users experienced psychotic symptoms after
|consuming cannabis. The highest rates were reported by experimental
|studies that administered tetrahydrocannabinol (THC), while the lowest
|(2%) were observed in studies assessing medicinal cannabis. The research
|was published in Nature Mental Health. In some individuals, cannabis
|use can lead to the development of psychotic symptoms, known as
|cannabis-associated psychotic symptoms. These symptoms can include
|hallucinations, delusions, and disorganized thinking, particularly in
|those predisposed to mental health issues. High doses of THC, the
|primary psychoactive compound in cannabis, are more likely to trigger
|these symptoms. While some people may experience these effects
|temporarily, in certain cases, cannabis use can trigger or exacerbate
|long-term psychotic disorders, such as schizophrenia. The results
|showed that the reported percentage of participants developing cannabis-
|associated psychotic symptoms varied greatly between studies. The share
|was highest in experimental studies, around 21%, high in observational
|studies at 19%, and lowest in medicinal cannabis assessment studies at
|2%. Individuals more likely to experience cannabis-associated psychotic
|symptoms included those who received THC, individuals with preexisting
|mental health issues, those with higher dopamine activity, younger
|individuals, and females.
|u/KuriousKhemicals - 1 month
|
|Well that tracks. You take a random population and administer just the
|most psychotogenic component, you get more of that. You take a
|population of people already self-selected for being interested in
|cannabis for therapeutic reasons and give full spectrum plant
|material, not so likely.
|u/appropriate_ebb643 - 1 month
|
|>These symptoms can include hallucinations, delusions, and
|disorganised thinking Symptoms or desired effect? Taoist monks were
|using it to bring on hallucinations thousands of years ago
|https://drugtimeline.ca/event/cannabis-was-added-incense-burners-
|ancient-china/
|u/T1Pimp - 1 month
|
|>Symptoms or desired effect? Taoist monks were using it to bring on
|hallucinations thousands of years ago No doubt some people use it
|for that (also... Rastafarians) but in this case they are talking
|about it in a VERY undesirable way. I'm a nightly cannabis user. I
|am in no way anti-cannabis at all. However, my brother-in-law
|*CANNOT* use it. At best it causes extreme disassociation. However,
|on the more extreme/awful end it spins him into suicidal ideation,
|he can hear voices, etc. The only thing that has saved him from
|cannabis is cannabis and the fact that edibles hit him so hard. The
|worst case was when we went missing... I found an empty container of
|gummies and then after hours I found him slumped against a tree with
|a shotgun in his hand and a weird ass note that barely made any
|sense. He just got knocked on his ass before he could off himself
|because he was inexperienced with edibles, so he kept taking more
|waiting for it to kick in.
|u/appropriate_ebb643 - 1 month
|
|I take edibles for my arthritis and have treble dosed by accident
|before. I went into an alternate reality for a while, full out of
|body experience, I was fine until I realised, and then had a
|massive whitey.
|u/T1Pimp - 1 month
|
|I use a volcano with a limiter/dosing caps/whip on it because
|I'm the only one who uses it. The fam was out of town one
|weekend, so I decided to really go to town and give the bags a
|try. um..... I tooooootally over did it. Unintentional and not
|pleasant. I was fine, of course, I knew "this will pass" but
|that didn't make the experience funsies for sure.
|u/dustymoon1 - 1 month
|
|Pretty useless study because they just looked at the use of not what
|these other studies were doing and what the people in the study had.
|It did discern people with alcohol, or other issues from taking THC or
|cannabis. They also didn't discern if the THC was purified, etc.
|nor how was it taken.
|u/marcok36 - 1 month
|
|Not cannabis user but assuming tolerance does build up and frequent
|users graduate to higher potency?
|u/Weird-Agile - 1 month
|
|How does this compare to other drugs or medications
|u/postmodernist1987 - 1 month
|
|Could there have been selection bias (potentially affecting the results)
|during the full-text screening when they went from 162 studies down to
|the 99 studies which reported data on rates of acute cannabis-associated
|psychotic symptoms? Risk of publication bias was assessed but I found no
|mention of selection bias.
|u/bubbs4prezyo - 1 month
|
|So? Just give Ambien to sleep, Paxil to feel happy, Xanax to calm down,
|Valium to help Xanax, and Adderall to get me going again.
|u/natefrog69 - 1 month
|
|A 19% swing between the study types is pretty crazy. Makes me wonder
|where funding for each study came from and if that had any influence in
|the results. I trust science, but I don't trust humans.
|u/Inevitable_Tip_2860 - 1 month
|
|What? This literally helps my stress,which decreases my psychotic
|tendencies. Idk if jerking off viciously is psychotic or not.
|u/Nathanael_ - 1 month
|
|Fwiw, since I have used psychedelics (lsd, mushrooms) - I feel that
|cannabis allows me to “access” similar hallucinogenic effects that I
|experienced on those stronger psychedelics. Psilocybin and LSD
|introduced me to this other “hallucinatory reality”, and now if I use
|cannabis, I can access this world with a little bit of focus or
|meditation. My point being, in the case with people experiencing
|psychotic symptoms with just cannabis, I can now understand why.
|u/RespondNo5759 - 1 month
|
|It is known, although not on how much extend, that CBD is a protector
|against psychosis, while THC promotes it. That's to say, when in a
|controlled trial, scientist tends to deliver pure THC with no CBD. On
|the other hand, observational studies on medicinal cannabis (pure plant)
|there is a good amount of CBD that prevents the psychosis from
|happening.
|u/slushhee - 1 month
|
|Yes, if you give five strangers a joint, watch them spark up and pass it
|around, you might see one of them get quiet and paranoid while the other
|four get more talkative and comfortable. This concept isn't new; people
|have always had adverse reactions to drugs.
|u/IWroteCodeInCobol - 1 month
|
|Everyone should be aware that ALL medicine, synthetic or natural will
|have side effects. Sometimes the side effects can be worse than the
|problem you are taking the medicine for. ALWAYS, watch for side effects
|when taking a new medicine. Worse yet, multiple medicines can combine
|to worsen side effects, create new side effects and even render the
|medicines useless. Always check with your pharmacist about
|possible side effects and drug interactions but be sure to let your
|pharmacist also know what supplements you are taking as well.
|u/santaclaws_ - 1 month
|
|> Cannabis use is associated with psychotic symptoms in between 2% and
|21% of users. And then they sober up and go back to work.
|u/Insta_boned - 1 month
|
|Don’t smoke Sativa if it makes you feel froggy
|u/Hot-Rub-2518 - 1 month
|
|Did the same people who did this study make the movie Reefer Madness?
|u/devadander23 - 1 month
|
|And now they’re in the comments
|u/SytzeL - 1 month
|
|All about the setting is what it seems like. I have felt this myself.
|Growing up in the Netherlands, where it’s fine for perfect use I never
|experienced any paranoia, but first time smoking in the US, knowing that
|it was illegal, made me super paranoid. Now with legalization everywhere
|that has gone away.
|u/dynamiteSkunkApe - 1 month
|
|2 and 21 percent is a pretty huge spread, you could sail and aircraft
|carrier through that
|u/Thisam - 1 month
|
|It reads like they assume medical marijuana doesn’t have THC…which it
|does. Assuming that maybe I misread that, there are still problems
|here. “Psychotic symptoms” need very clear clinical definitions and
|cannot be anecdotal reports from people who get high whether they’ve
|ever felt anxious…. Everyone has but that’s not really surprising nor
|concerning. Of course marijuana causes some “psychotic symptoms”, but
|just as part of the high. Another bit of “research” funded by the anti-
|weed lobby?
|u/t0sspin - 1 month
|
|oK bUt WeRe ThE sUbJeCtS pSyChOtIc To BeGiN wItH…? Surely it’s just a
|matter of people who were already psychotic gravitating toward
|using/self-medicating with cannabis… surely!! Surely cannabis can’t
|actually be bad, can it? It’s just a plant!!!!! Right guys!?
|u/QueSeraShoganai - 1 month
|
|What a strange comment. Are you implying that your first question
|isn't an important one when performing these studies?
|u/t0sspin - 1 month
|
|Every time there’s a post associating cannabis and psychosis or poor
|mental health people on Reddit flock to it to defend cannabis and
|try to (at least partially) basically frame the conclusions of the
|studies as mentally ill people medicating with cannabis. I can
|tell you as someone who used cannabis as an adolescent and developed
|permanent cognitive impairment from it with no history of mental
|illness, no predisposition to mental illness, and nothing else other
|than a direct cause and effect with cannabis the way people approach
|this and push that narrative is harmful. This happened to other
|people i know as well. For the record, I’m not saying mentally ill
|people don’t ever self medicate with cannabis, my issue is using
|this conclusion to discredit evidence cannabis causes mental/
|cognitive issues because you don’t want to accept cannabis is
|harmful is wrong.
|u/Effective-Lab2728 - 1 month
|
|Note that the lower end of the range doesn't come up with a higher
|prevalence of psychotic symptoms in the medical marijuana group vs
|what occurs in the general US population, which tends to come out
|at 3-5%.  The extract study is clearly much higher at 21%, but
|suggesting the medical marijuana studies are so unambiguous that
|anyone who thinks otherwise is deluding themselves just doesn't
|seem fair when it seems you are basing this on personal anecdote
|rather than engaging with the statistics.
|u/t0sspin - 1 month
|
|>Participants in observational and experimental studies were
|primarily in their 20s and 30s, while the average age of
|individuals in medicinal cannabis assessment studies was 48
|years. Note that the lower end (the 2%) is specifically among
|medical cannabis users, which they note as being in people with
|an average age of 48. The people who experience psychosis at the
|much higher rate were primarily in their 20s and 30s which is
|significantly younger, and I am willing to bet that the largest
|non-mentioned demographic in observational and experimental
|studies would be in their teens. Of course this is speculation,
|but I would imagine those would represent a significant portion
|of the 21% and 19% respectively. Basically, "old" people are
|less susceptible to experiencing psychosis. Speculatively, this
|is because old people's brain structure/chemistry is more
|established, stable, robust, and thus resilient to the effects
|of THC vs younger people who are more susceptible to having
|their brain function thrown off. It's possible the 2% of old
|people who get psychosis from cannabis may have had underlying
|issues in line with the proportion of issues in the general
|population It seems to be a direct association between between
|"young" people developing psychosis from cannabis use actually
|supports my and many others "anecdotes". And for the record,
|reliable anecdotes are important.
|u/Effective-Lab2728 - 1 month
|
|To be clear, I am not calling your anecdote useless. I'm
|calling it insufficient grounds to mock others for finding the
|statistics ambiguous at this point for causally connecting
|cannabis use to a higher risk of psychotic disorders. I have
|my own anecdote of depressive episodes deep enough to trigger
|psychotic symptoms at their worst, then eventually finding
|cannabis made depression much easier to control, thus
|preventing further spirals toward psychosis. I wouldn't
|suggest that this is unambiguous evidence for cannabis in the
|treatment of recurrent major depressive disorder. The age
|issue may well complicate the data's interpretation, making 
|further study of more mindfully selected age groups
|worthwhile. That still doesn't make this a clear cause and
|effect.
|u/t0sspin - 1 month
|
|My issue is the criticism and dismissal of the science/data
|comes from people who are biased toward their own
|(perceived) positive experience with cannabis and my belief
|is this approach is actually quite harmful. I understand I
|have my own bias as a result of my negative experience, but
|for the most part when it comes to discussing studies
|(positive or negative) I tend to explain my own experience
|and how it warrants further investigation. people using
|cannabis isn’t my concern. What I care about is people
|having fully informed consent of the potential consequences
|and for the science to progress to the point harm can be
|totally mitigated and ideally reversed.
|u/Effective-Lab2728 - 1 month
|
|I can't say the extremely long period of assuming it to be
|unambiguously harmful (to both users and those around
|them) was without its own harms. I agree that
|discouraging caution is a harmful behavior, and I do push
|back against those who minimize data regarding dependency.
|I do also agree that your experience is worth sharing. 
|That said, you'll notice people pipe up to remind everyone
|of the the difference between correlation and causation on
|every other study posted here, regardless of subject, as
|it's one of those easy things to remember that's also easy
|to forget the moment you think you have a really good
|sense of something. They're usually not wrong to do so.
|u/bbcendo - 1 month
|
|Compare it with alcohol and THC will win
|u/mrmczebra - 1 month
|
|This isn't a drug shootout. There's no reason to compare.
|u/AntiDECA - 1 month
|
|Win what? All that means is alcohol also is bad for you.. Which we've
|known for quite some time. 
|u/Low_Distribution3628 - 1 month
|
|K, doesn't mean it's not dangerous.
|u/Wetschera - 1 month
|
|Isn’t just 2% a huge number in terms of statistics?
|u/Redbeard4006 - 1 month
|
|I couldn't get through the article without being redirected to scams and
|porn ads. It was my understanding that CBD was somewhat protective, so
|high doses of THC with low to no CBD was much riskier than high THC and
|moderate to high CBD. Was this addressed in the article? Is this
|correct?
|u/LaGeG - 1 month
|
|Recent studies have shown that CBD doesn't actually seem to have any
|protective effects and they found some evidence that in some ratios it
|might even enhance the effects of THC
|u/Redbeard4006 - 1 month
|
|Thank you. I appreciate the update.
|u/bubbs4prezyo - 1 month
|
|Excluding anti inflammatory and antioxidant benefits….
|u/Chrijopher - 1 month
|
|Cbd been shown to have negative effects in pregnancy 
|u/breakfastmeat23 - 1 month
|
|Take these studies with a huge grain of salt, the pharmaceutical
|industry desperately wants to get control of cannabis now that it is
|becoming legal.
|u/danis1973 - 1 month
|
|Wow r/science brining some anti-cannabis studies this week. Its good to
|know the risks of any consumption activity but imma go ahead and keep
|smoking my lifeblood
|u/Warm_Iron_273 - 1 month
|
|Keep glorifying recreational drug use, fostering addiction, I'm sure
|it'll help your nation develop.
|u/External_Hedgehog_35 - 1 month
|
|Has anybody tracked an equivalent percentage of alcohol users? How many
|people (what percentage) of alcohol users exhibit psychotic symptoms?
|The pot study needs to be significantly worse to make the information
|valid or actionable. This feels like a lot of cannabis related studies:
|thinly veiled attempts to scare monger. We now have years of data to
|work from. Is mental illness, dui s, drug addiction worse in states
|where pot is legal? Most reports I see show those going down with a
|bonus that opiod addiction plummets in states with legal cannabis. And
|isn't that a wide range for a study? 2 to 20 per cent? Couldn't narrow
|that down? Not saying no risk to pot consumption,  just do better with
|the data.
|u/punkalunka - 1 month
|
|What the hell is with all these negative cannabis experiments?
|u/Guypersonhumanman - 1 month
|
|We shoved 162 studies with different variables together to highlight our
|position 
|u/inlandviews - 1 month
|
|It comes across as propaganda. I've read several of these in the last
|week and they all have the similar preambles .A metastudy of studies
|all trying to show how dangerous cannabis is. It brings out the usual
|tropes. THC of old was low concentration and the modern strains are so
|high and therefore more dangerous. It belies the fact that higher
|concentrations mean you consume less substance to get where you want to
|get to. I've consumed cannabis since 1972 and I can tell you
|Afghanistan, Thailand and Columbia were producing strains in the 70s
|that knock the socks off modern ones. I've known hundreds of cannabis
|users and only one ever reported a feeling of paranoia and he never did
|it again. Problem solved. I'll take these studies with a grain of
|salt.
|u/Icy-Gap2745 - 1 month
|
|Psychotic? Or tired with the normal humdrum of life and finally seeing
|what is real?
|u/FIalt619 - 1 month
|
|Does it matter what you call it? If you don’t have a way to cope with
|reality, in all its shittiness, then you don’t have a lot of good
|options.
|u/ChemistFar145 - 1 month
|
|There should be a way to create a cannabis substance that is safe for
|users.
|u/Khuros - 1 month
|
|Unusual number of biased articles being pushed to this sub.
|u/Specialist_Cause9741 - 1 month
|
|Psychosis mostly comes to life in individuals with severely compromised
|health status , the cannabis can be the cherry on top. But the real risk
|factors is the severely weakening of the body, reflected back in the
|psyche. Lack of sleep, use of stimulants, lack of carbohydrates in diet
|causing chronic stress, unnatural circadian rhytm, not eating breakfast,
|etcetera.
|u/cokepatron - 1 month
|
|can we talk about how fun being psychotic can be
|u/Silverwell88 - 1 month
|
|It's pretty rare to have fun with psychosis. I have schizophrenia and
|have experienced a crap ton of psychosis and it's hands down the worst
|experience of my life. It's absolute torture and trauma.
|u/myjohnson6969 - 1 month
|
|Its no different for prescribed opiods, or alchohol
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